Cabotegravir Injection/Rilpivirine Injection (CABOTEGRAVIR/RILPIVIRINE EXTENDED-RELEASE - INJECTION)

Instructions

This medicine will be given to you at the doctor's office.

This medicine is given as an injection into a muscle.

This medicine should be given by a trained health care provider.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

This medicine passes into breast milk. Ask your doctor before breastfeeding.

Do not breastfeed while on this medicine.

Do not take St. John's wort while on this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• agitated feeling or trouble sleeping
• dizziness
• changes in areas of body fat may alter your body shape
• lack of energy and tiredness
• bruising, bumps, or hardened skin at the injection site
• pain, redness, swelling near injection
• lightheadedness
• nausea
• sweating

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• loss of balance
• cough that does not go away
• depression or feeling sad
• bulging eyes
• fever or chills
• severe or persistent headache
• fast or irregular heart beats
• irritability
• pain in the joints
• signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
• muscle pain or weakness
• unusual growth or lump on the neck
• nervousness
• red, burning, or itchy skin
• shortness of breath
• difficulty speaking
• stomach pain
• suicidal thoughts
• difficulty swallowing
• difficulty adjusting to changes in temperature
• sudden or unexplained weight gain
• slow wound healing

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.