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Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Alafenamide Oral Tablet (ELVITEGRAVIR/COBICISTAT/EMTRICITABINE/TENOFOVIR ALAFENAMIDE - ORAL)

For HIV.

Brand Name(s): Genvoya

Generic Name: Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Alafenamide

Instructions

Keep the medicine in its original container.

Take the medicine with food.

Do not take on an empty stomach.

Swallow with a full glass (8 oz) of water unless your doctor gives you different instructions.

This medicine will work best if you take it at about the same time every day.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

Always use condoms during sex.

Do not share needles or other personal objects such as shavers or toothbrushes.

Do not take any medicine containing calcium, magnesium, aluminum, bismuth, zinc or iron (such as antacids, vitamins, quinapril, didanosine, sucralfate) for 2 hours before or 2 hours after this medicine.

Do not take antacids 2 hours before or 2 hours after taking this medicine.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Keep using this medicine for the full number of days that it is prescribed. Do not stop the medicine even if you start to feel better.

This medicine may decrease the effectiveness of some birth controls which use hormones (such as birth control pills and patches). Use an extra form of birth control, such as condoms, while on this medicine.

Use effective birth control to avoid pregnancy.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

This medicine is associated with a rare, but serious problem of the liver. Speak to your doctor about the early signs of liver problems and the benefits and risks of using this medicine.

Do not use the medication any more than instructed.

Please check with your doctor before drinking alcohol while on this medicine.

Talk to your doctor about getting a complete physical exam every year while on this medicine.

Use condoms to reduce the risk of sexually transmitted diseases.

Contact your doctor if you notice a change in the amount or darkening of your urine.

Contact your doctor if you develop any signs of a new infection such as fever, cough, sore throat, or chills.

Wash your hands often and avoid close contact with people with infections such as colds and flu.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

This medicine passes into breast milk. Ask your doctor before breastfeeding.

Do not take this medicine with other medicines called PDE5 inhibitors (Viagra, Levitra, Cialis). Your doctor will let you know if it is safe for you to do so.

Do not take St. John's wort while on this medicine.

Do not share this medicine with anyone who has not been prescribed this medicine.

Always refill this medicine before it runs out.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • diarrhea
  • lack of energy and tiredness
  • headaches
  • nausea

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • decreased appetite
  • drowsiness or sedation
  • fever or chills
  • swelling in the neck or throat
  • numbness or tingling in hands and feet
  • severe or persistent headache
  • fast or irregular heart beats
  • irritability
  • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
  • loss of movement anywhere on the body
  • tight or rigid muscles
  • muscle weakness
  • joint or muscle pain
  • shortness of breath
  • difficulty speaking
  • severe or persistent vomiting
  • unexpected or extreme weight loss

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.