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Prochlorperazine Rectal Suppository (PROCHLORPERAZINE - RECTAL)

For nausea or vomiting.

Brand Name(s): Compazine, Compro

Generic Name: Prochlorperazine

Instructions

This medicine is for use in the rectum. DO NOT take this medicine by mouth.

Wash your hands before and after using this medicine. However, do not get up right away to wash your hands if you are supposed to lie down for a period of time to give the medicine time to work.

Lie on your left side, with your right knee bent toward your chest. Or, you may kneel on both knees, with your arms folded on the floor with your head resting on your arms.

Unwrap the suppository and moisten it with a few drops of cool water. Insert the pointed end into the anus, and push it all the way in with your finger.

Keep the medicine at room temperature. Avoid heat and direct light.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

This medicine can make you sensitive to the sun. Use sunscreen or protective clothing when in sun.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Tell your doctor if symptoms do not get better or if they get worse.

You may stop using this medicine if you no longer have symptoms.

It is very important that you follow your doctor's instructions for all blood tests.

Do not freeze the medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

This medicine is associated with a rare but very serious medical condition. Please speak with your doctor about symptoms you should look out for while on this medicine. Notify your doctor immediately if you develop those symptoms.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Do not use the medication any more than instructed.

This medicine may cause dizziness or fainting. Do not stand or sit up quickly.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

If you drink alcohol regularly, please speak with your doctor.

Avoid becoming overheated during exercise or other activities. Try to stay cool in hot weather.

Contact your doctor if you notice a change in the amount or darkening of your urine.

Call the doctor if there are any signs of confusion or unusual changes in behavior.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • constipation
  • dizziness or drowsiness
  • dry mouth
  • low blood pressure
  • menstruation changes (missed or fewer periods)
  • red, burning, or itchy skin
  • problems with sexual functions or desire
  • vivid dreams or nightmares

If you have any of the following side effects, you may be getting too much medicine. Please contact your doctor to let them know about these side effects.

  • agitated feeling or trouble sleeping
  • loss of balance
  • difficulty concentrating
  • confusion
  • muscle trembling or weakness
  • restlessness
  • difficulty swallowing
  • unsteadiness while walking
  • difficulty or discomfort urinating
  • blurring or changes of vision

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • decreased awareness or responsiveness
  • high fever
  • fast or irregular heart beats
  • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
  • uncontrollable movement of face, tongue, arms or legs
  • muscle aches, spasms or abnormal movements
  • seizures
  • light colored stool

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.